Product name: Enbrel

Manufacturer: Amgen (Pfizer) & Wyeth Pharmaceuticals

Active substance: Etanercept

Strength(s): 4 Cartridges of 50MG, 4 Mini Cartridges of 50MG, 4 Sureclicks of 50MG, 4 Syringes of 25MG, 4 Syringes of 50MG, 4 Vials of 25MG

Quantity: 1-45 Cartons of Cartridges, Mini Cartridges, Sureclicks, Syringes & Vials (4 each in a Carton)

In stock




What is Enbrel?

Etanercept is an injectable drug that is used for treating rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and plaque psoriasis.

It works by blocking tumor necrosis factor alpha (TNF alpha). Other drugs that block TNF alpha include adalimumab (Humira), certolizumab (Cimzia), golimumab (Simponi), and infliximab (Remicade).

TNF alpha is a protein that the body produces during when there is inflammation, the body’s reaction to injury. TNF alpha promotes inflammation and its associated fever and signs (pain, tenderness, and swelling) in several inflammatory conditions including rheumatoid arthritis and ankylosing spondylitis. Etanercept is a synthetic (man-made) protein that binds to TNF alpha. It thereby acts like a sponge to remove most of the TNF alpha from the joints and blood. This prevents TNF alpha from promoting inflammation and the fever, pain, tenderness, and swelling of joints in patients with rheumatoid or psoriatic arthritis and ankylosing spondylitis. Etanercept prevents the progressive destruction of the joints in patients with rheumatoid arthritis and the arthritis of psoriasis. The FDA approved etanercept in November 1998.

Enbrel (etanercept) is a tumor necrosis factor (TNF) blocker. It works by decreasing TNF, a protein produced by the immune system to helps the body fight infections. In people with autoimmune disorders, the immune system produces too much TNF and mistakenly attacks healthy cells.

Enbrel is used to treat rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis, and to prevent joint damage caused by these conditions.


Side effects of etanercept?

The most common side effects are:

mild to moderate itching,


swelling and redness at the site of injection,



nasal and throat.


Important information to be considered before consumption

Etanercept is injected under the skin.

Adult rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis: 50 mg weekly

Plaque psoriasis: 50 mg twice weekly for 3 months, followed by 50 mg once weekly

Juvenile rheumatoid arthritis: 0.8 mg/kg weekly, with a maximum of 50 mg per week


Important information to be considered before consumption

You should not use Enbrel if you are allergic to etanercept, or if you have a severe infection such as sepsis (infection of the blood).

To make sure Enbrel is safe for you, tell your doctor if you have:

a weak immune system, HIV or AIDS, tuberculosis, or any type of recurring infection;

symptoms of an active infection such as fever, flu symptoms, diarrhea, or painful urination;

an open cut or skin sores;


congestive heart failure;

a history of nerve disorders such as multiple sclerosis, Guillain-Barré syndrome, myelitis, or optic neuritis;

epilepsy or other seizure disorder;

asthma or other breathing disorder;

if you have ever had hepatitis B;

if you are allergic to latex rubber; or


Enbrel drug interactions

Most frequently checked interactions

View interaction reports for Enbrel (etanercept) and the medicines listed below.

Aleve (naproxen)




Benadryl (diphenhydramine)

Celebrex (celecoxib)

Cymbalta (duloxetine)

Fish Oil (omega-3 polyunsaturated fatty acids)

folic acid


Humira (adalimumab)




Lyrica (pregabalin)



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