Product name: Ocrevus

Manufacturer: Hoffmann–La Roche

Active substance: Ocrelizumab

Strength(s): 10mL of 30MG/mL

Quantity: 1-45 Vials

In stock




What is Ocrevus?


Ocrevus (ocrelizumab) is a monoclonal antibody that affects the actions of the body’s immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

Ocrevus is used to treat multiple sclerosis (relapsing or progressive forms) in adults.

Ocrevus may also be used for purposes not listed in this medication guide.


Important information

Ocrevus may cause unpleasant side effects while the medicine is injected, or up to 24 hours later. Tell your caregivers if you have unpleasant side effects such as dizziness, nausea, skin rash, chest tightness, or trouble breathing within 24 hours after your injection.

Ocrevus affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, cough, mouth sores, skin sores or blisters, itching, tingling, burning pain, or problems with speech, thought, vision, or muscle movement.

If you’ve ever had hepatitis B, it may become active or get worse while you are using or after you stop using ocrelizumab. You may need frequent liver function tests for several months.


Before taking this medicine

You should not be treated with Ocrevus if you are allergic to ocrelizumab, or if you have:

active infection with hepatitis B.

Your doctor may perform tests to make sure you do not have hepatitis B or other infections.

You should not receive any “live” or “live-attenuated” vaccine, within the 4 weeks before you start treatment with Ocrevus. If you need a “non-live” vaccine, you should receive it at least 2 weeks before you start treatment with ocrelizumab.

Also tell your doctor if:

you have any type of active infection;

you are a carrier of hepatitis B; or

you have ever used medicine that can weaken your immune system.

Using Ocrevus may increase your risk of developing certain types of cancer, such as breast cancer. Ask your doctor about your specific risk.


Side effects

Get emergency medical help if you have signs of an allergic reaction to Ocrevus: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection or up to 24 hours later. Tell your caregiver right away if you feel dizzy, sleepy, nauseated, light-headed, feverish, sweaty, itchy, or have a red skin rash, headache, fast heartbeats, chest tightness, trouble breathing, or swelling and irritation in your throat.

Call your doctor at once if you have:

fever, chills, cough with yellow or green mucus;

stabbing chest pain, wheezing, feeling short of breath;

skin warmth, redness, itching, or swelling;

skin sores, blisters, pus, or oozing;

cold sores or fever blisters on or around your lips;

nerve pain (tingling, burning pain, “pins and needles” feeling);

mood or behavior changes, confusion, memory problems;

weakness on one side of your body; or

problems with vision, speech, or muscle movement.

Your treatments may be delayed or permanently discontinued if you have certain side effects.

Common Ocrevus side effects may include:

skin infections;

reactions to an injection; or

cold symptoms such as stuffy nose, sneezing, sore throat.


Ocrevus drug interactions

Most frequently checked interactions

Ocrevus is known to interact with the medicines listed below.


Ampyra (dalfampridine)





Copaxone (glatiramer)

Cymbalta (duloxetine)

Fish Oil (omega-3 polyunsaturated fatty acids)



Lyrica (pregabalin)

magnesium oxide





Rituxan (rituximab)



Vitamin B12 (cyanocobalamin)

Vitamin D3 (cholecalciferol)



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