600.00$ – 17,200.00$
Product name: Orkambi
Manufacturer: Vertex Pharmaceuticals
Active substance: Lumacaftor/Ivacaftor
Strength(s): 100MG/125MG, 200MG/125MG
Quantity: 30-750 Tablets
ORKAMBI FOR SALE ONLINE
What is Orkambi?
Orkambi contains a combination of ivacaftor and lumacaftor. Ivacaftor and lumacaftor is used to treat cystic fibrosis in adults and children who are at least 2 years old.
Orkambi is for use only in patients with a specific gene mutation related to cystic fibrosis.
Before you take Orkambi, you may need a medical test to make sure you have this gene mutation.
Orkambi can cause serious side effects. High liver enzymes in the blood, which can be a sign of liver injury, have been reported in patients receiving this medicice. Your doctor will do blood tests to check your liver.
Serious drug interactions can occur when certain medicines are used together with Orkambi. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Before taking this medicine
You should not use Orkambi if you are allergic to ivacaftor or lumacaftor.
Some medicines can cause unwanted or dangerous effects when used with ivacaftor and lumacaftor. Your doctor may change your treatment plan if you also use:
rifabutin or rifampin;
St. John’s wort;
medicine to prevent organ transplant rejection – cyclosporine, everolimus (Zortress), sirolimus, tacrolimus;
a sedative – triazolam or midazolam; or
seizure medicine – carbamazepine, phenobarbital, phenytoin.
To make sure Orkambi is safe for you, tell your doctor if you have ever had:
high blood pressure;
asthma or other lung disease; or
an organ transplant.
Get emergency medical help if you have signs of an allergic reaction to Orkambi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
shortness of breath, tightness in your chest; or
liver problems – nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common Orkambi side effects may include:
nausea, gas, diarrhea;
changes in your menstrual periods; or
cold symptoms such as runny or stuffy nose, sinus pain, sore throat.
Orkambi drug interactions
Most frequently checked interactions
Orkambi is known to interact with the medicines listed below.
Humalog (insulin lispro)
Hyper-Sal (sodium chloride)
Peri-DS (casanthranol / docusate)
ProAir HFA (albuterol)
Pulmozyme (dornase alfa)
Symbicort (budesonide / formoterol)
Vitamin D3 (cholecalciferol)
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